FDA Green-Lights Clinical Trial For COVID-19 Coronavirus Treatment That ‘Flattens The Curve’ In Patients

FDA Green-Lights Clinical Trial For COVID-19 Coronavirus Treatment That ‘Flattens The Curve’ In Patients

Therapeutics startup Celularity announced Thursday morning that it has received FDA clearance to begin a clinical trial of a proposed stem-cell treatment for COVID-19. The approval of the New Jersey-based company’s IND application enables the company to begin a clinical trial with patients who have the disease.

The company’s therapy, called CYNK-001 for now, uses “Natural Killer” (NK) cells, a form of white blood cells that wage war against cancer and viral infection, derived from placental stem cells. The company’s been developing similar treatments for several years against cancer and Crohn’s disease, several of which are being tested as well.

Source: https://www.forbes.com/sites/alexknapp/2020/04/02/fda-gives-green-light-to-test-a-treatment-against-covid-19-coronavirus-that-flattens-the-curve-in-patients/#d684b3e4b572/

COVID-19 Adult Stem-Cell Trials

COVID-19 Adult Stem-Cell Trials

The pulmonary function and symptoms of these seven patients were significantly improved in 2 days after MSC [Mesenchymal stem cells] transplantation. Among them, two common and one severe patient were recovered and discharged in 10 days after treatment. After treatment, the peripheral lymphocytes were increased, the C-reactive protein decreased, and the overactivated cytokine-secreting immune cells CXCR3+CD4+ T cells, CXCR3+CD8+ T cells, and CXCR3+ NK cells disappeared in 3-6 days.

The intravenous transplantation of MSCs was safe and effective for treatment in patients with COVID-19 pneumonia, especially for the patients in critically severe condition.

Source: https://www.nationalreview.com/corner/covid-19-adult-stem-cell-trials/

Could stem cells treat COVID-19?

Could stem cells treat COVID-19?

DENVER (KDVR) — A small study in China has some Colorado doctors promoting the use of umbilical stem cells to treat COVID-19 patients.

“Seven patients got the umbilical cord stem cells, three got placebos. All seven of the patients who were treated – and these are severe and critically severe patients – every last one of them got off the ventilator and walked out of the hospital,” said Dr. Scott Faulkner, an internal medicine doctor at Grand River Hospital in Rifle, Colorado.

Source: https://kdvr.com/news/coronavirus/could-stem-cells-treat-covid-19/

First cell treatment to fight the coronavirus awaits FDA approval for clinical trial

First cell treatment to fight the coronavirus awaits FDA approval for clinical trial

  • New Jersey-based therapeutics company Celularity is awaiting permission from the FDA to test whether a cancer treatment could be effective against COVID-19.
  • The cell therapy works by boosting the body’s early immune response in a way that could target the coronavirus.
  • The company transforms placental stem cells into one-size-fits-all “Natural Killer” cells that act as sentinels and keep the virus from replicating out of control.
  • Some researchers caution that the strategy is highly uncertain and potentially risky, but if the treatment proves safe and effective, Celularity will ramp up production quickly.

Source: https://www.cnbc.com/2020/03/31/cell-therapy-to-fight-covid-19-awaits-fda-approval-for-clinical-trial.html

Regenerative Medicine & Pain Management Specialist

Regenerative Medicine & Pain Management Specialist

This article was written with the help of Dr. John Serpa, who is an integral part of our Team of Experts at Miami Stem Cell® and is certified by the American Board of Anesthesiology with Sub-specialty Certification in Pain Management from the prestigious Cornell University in New York. In addition, Dr. Serpa possesses tremendous expertise in Regenerative Medicine and the Stem Cell Therapy arena. Having a true passion for practicing medicine, Dr. Serpa has received numerous awards and accolades that have made him extremely well-known in the South Florida community as “the doctor with the golden hands”, a true testament to his post-procedure now famous coined phrase: “Today I Have No Pain®!”

When people are experiencing excruciating joint pain and have already unsuccessfully tried several options including: exercising, multiple physical therapy sessions, holistic medicine, opioid medications, change of diet, taken supplements and exhausted all their alternatives, at that point, there are basically only two choices left: Joint Replacement Surgery or Stem Cell Therapy.

In recent years, there have been dramatic advances in Stem Cell Therapy which have basically revolutionized how cutting-edge physicians now manage pain more efficiently. Dr. Serpa believes that in less than five years, Health Insurance companies will be forced to cover Regenerative Medicine procedures, not only because patients and their families are becoming more educated about these treatments, but also based on an increasing number of reliable scientific studies that validate their effectiveness. Stem Cell Injections on elderly patients (70 and older) have proven to be a viable solution to control their pain and improve their overall quality of life, all without the risks involved with an invasive surgery.

One of my favorite patient stories is the one about a 96 year old lady that came in for a consultation (assisted by a walker) about seven years ago and even though we explained to her that (at the time) we only had in-house data about the effectiveness of Stem Cell Therapy up to a 90 year old, she insisted in being evaluated by our Team of Experts. In addition, the patient’s daughter basically begged us to perform the treatment on her mom (mostly because her cardiac condition could not allow her to undergo a major knee replacement surgery) so we then proceeded to perform an Autologous Stem Cell Transplant from her bone marrow and surprisingly, in the patient’s first follow up (6 weeks after the procedure) this 96 year old patient came into our office without the need of her walker!

Currently, this procedure is an important part of our history and subsequently we have successfully treated thousands of elderly patients (from 70 to 102 years old) since then. In addition, we now also boost the effects of this non-invasive Stem Cell Treatment by adding the latest in Biological Products. While to this day, there are still various conflicting views on the effectiveness of Stem Cell Therapy on patients older than 70, we have thousands of cases in our database that prove otherwise.

In conclusion, Stem Cell Therapy far outweighs in benefits when compared to the many risks related to having surgery, particularly in these key areas:

  • No Hospitalization Required / Stem Cell Treatments are conducted in only a few hours and the patient gets to go home right after the procedure.
  • No Risk of Infection / Stem Cell Therapy uses Autologous Stem Cells collected from your own body.
  • No Risk of General Anesthesia / Stem Cell Treatments only use localized minimal sedation.
  • Shorter Recovery / Down Time since the recovery process for Stem Cell Therapy is much easier and shorter than surgical recovery. Most patients do not experience any pain or swelling after 24 hours. This means you can quickly return to your normal life.
  • Requires much less post-procedure pain medication.

Miami Stem Cell® continues to be at the forefront in the clinical application of Stem Cell Treatments in America and we effectively treat a wide variety of conditions with minimally invasive procedures that include:

  • Arthritis (pain in the knee, shoulders, hips, spine, cervix and other joints).
  • Sports injuries (Tennis Player’s Elbow, Golfer’s Shoulder, etc.).
  • Degeneration of lumbar discs / Sciatica and pain in the lower back.
  • Fibromyalgia.
  • Tendinitis / Carpal Tunnel.
  • Sexual dysfunction in men and women.
  • Congestive Heart Disease.
  • Coronary artery disease.
  • Peripheral Vascular Condition.
  • Asthma / COPD / Respiratory problems.
  • Urinary incontinence.
  • Hair restoration.
  • Facial, neck and hand rejuvenation.
  • Intravenous Multi-Vitamin infusions.
  • Micro-Nutritional Testing / Micro-Nutrition.

So if you are interested in learning more about this state-of-the-art Stem Cell Treatment modality or to schedule a free consultation with Dr. John Serpa, who is part of our acclaimed Team of Experts, please call Miami Stem Cell® at (305) 598-7777 or contact us via email at info@stemcellmia.com

You can also visit our website www.stemcellmia.com or. follow us on Facebook, Instagram & Twitter, as well as watch our amazing testimonial videos on our YouTube channel.

Give Stem Cells a Try Before Undergoing an Invasive Joint Surgery!

Give Stem Cells a Try Before Undergoing an Invasive Joint Surgery!

Miami Stem Cell® continues to be at the forefront in Stem Cell Therapy advancements and in this article, I will discuss in detail why treating joint related pain with Regenerative Treatments first and often even in lieu of surgery, can be extremely beneficial and should always be the primary option you try before undergoing certain types of invasive surgical procedures.

On a daily basis, we continue to see a myriad of patients that come to us complaining about joint pain even after having had surgery, a large percentage of them suffering with back / spine pain related issues in particular. Therefore, my objective here is to reiterate the importance of understanding that if a patient already has a titanium implant on their back (or basically any other foreign object implanted on another joint), our doctors would be somewhat limited to further treat your existing pain.

In the case of the spine (a critical area and prime example of what I am trying to convey here), our treatments are restricted to only certain specific areas that they can target after a surgical procedure, since we could not treat the actual titanium implanted vertebrate and thus, lessening the powerful benefits of our Regenerative Medicine Treatments. In addition, invasive surgeries involve many correlated troublesome issues, like the risk of general anesthesia, health complications, required extensive physical therapy sessions and also long periods of downtime, all of which could be avoided using our non-invasive Stem Cell Therapy option.

When a patient is considering the use of Regenerative Treatments such as Platelet Rich Plasma (PRP), Bone Marrow Aspirate (BMAC), commonly called ‘Stem Cells’ or mixtures with Biological products for treatment, the amount needed and location of the injection depends on the part of the body treated. Research evidence shows that injected biologics have a mixture of multiple cellular growth factors that work by ‘boosting’ the body’s healing of the injured area through accelerated but very localized inflammation in the site injected ultimately leading to tissue healing. Soft tissue such as muscle, tendons, capsules of joints and parts of the intervertebral disc are the targets for this type of treatment.

The spine in particular is different than larger joints such as the knee, shoulder or hip in several important ways. First, these are larger joints that are easier to localize and inject, have mainly tendons running within them that can partially or completely torn which is best suited for biologic treatments. Larger quantities of biologic material can be easily injected in these areas. However, in the spine there are 3 additional critical factors whether in the low back (lumbar) or neck (cervical). First, each vertebral segment includes an intervertebral disc as well as 2 small joints (facets) on each side at each level so in the spine this can degeneration frequently occurs in multiple joints. Second, the nerve roots are located between the disc and the joints and the spinal cord in the neck and nerve sac (dural sac) in the lumbar spine is important and then precise placement of the injection is critical and should be performed only by a specialist with spine training and not who does occasional injections in this area. Therefore, it is critical that the patient have up to date diagnostic films including plain X-rays and MRI scan and possibly even a CT scan, so the spine specialist can locate the exact site of the pathology and discuss with the patient whether it is local to one area or side or more general. Since it is the small spinal joints, their surrounding tissue and the intervertebral discs that are targeted, biologics are more effective before severe degeneration and bone overgrowth occurs which can be seen on these radiologic studies. The goal of the treatment is to both decrease pain and allow some resolution of the soft tissue swelling of the disc and joints.

In conclusion, the cellular immunotherapy space has exploded over the past few years and we are now entering the cell therapy revolution. The progress in this space has been unprecedented and Miami Stem Cell® has always been at the forefront using the latest technology and state-of-theart procedures to control pain.

So don’t delay and start living pain free today! For more information on the array of services we offer, or to schedule a free evaluation with our Team of Experts, please call Miami Stem Cell® at (305) 598-7777 or visit: www. stemcellmia.com You can also follow us on Facebook, Instagram & Twitter as well as watch our amazing testimonial videos on our YouTube channel or email us at: info@miamistemcell.co